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Enlarged neurons not susceptible to ‘Alzheimer’s knots’
The larger neurons in the brains of sharp-minded people over the age of 80 do not appear to have Alzheimer’s ganglia. These nodes are made up of cross-linked tau proteins – a hallmark of Alzheimer’s disease.
Enlarged neurons can maintain their structure and maintain their health. So it ensures that no knots are formed. As a result, the research team concluded that the synaptic tau proteins cause the neurons to shrink. Therefore, in Alzheimer’s disease, there is a state of shrinkage of neurons in the inner spinal cortex.
Future research should show why large neurons are not attacked by synaptic tau proteins and therefore do not contract.
